| Samantha's mother Ninette is from Kerala and her father Joseph is from Andhra Pradesh. |
| She was a top student in school. |
| To earn extra money, Samantha began modeling at a young age due to her family's financial situation. |
| A filmmaker noticed Samantha during a modeling assignment and offered her a role in a film. |
| Samantha participated in various fashion shows as a model. |
| She has worked with renowned photographers for photoshoots. |
| Samantha has appeared in TV commercials for several brands and print ads for brands like South India Shopping Mall, Rexona, and Drools. |
| Her acting career includes Tamil films like 'Super Deluxe' and Telugu films like 'A Aa' and 'Shaakuntalam'. |
| Samantha appeared in the Tamil music video "Semmozhiyaana Thamizh Mozhiyaam" by A. R. Rahman in 2010. |
| She began dating actor Naga Chaitanya in 2014 while filming 'Autonagar Surya'. |
| Aside from acting, Samantha founded an NGO named Pratyusha Support to provide medical aid to underprivileged women and children. |
| Samantha organized a plane trip to the Taj Mahal for children supported by her NGO in 2014. |
| In 2015, she collaborated with Andhra Pradesh Hospitals to cover a portion of an infant's weekly medical bills. |
| The Income Tax Department searched her home in 2015 along with other South Indian actors' residences. |
| Samantha expressed willingness to decrease her fees for significant film roles. |
| She established Tweave in 2017 to promote handloom in Telangana. |
| Samantha got engaged in 2017 and became a partner at SVS Partners LLP. |
| In 2020, she co-founded the preschool Ekam. |
| She has hosted TV shows like 'Bigg Boss Season 4' and 'Sam Jam'. |
| Samantha appeared in the popular song "Oo Antava Mawa" from the film 'Pushpa: The Rise' in 2021. |
| In 2021, Samantha and Naga Chaitanya announced their separation on Instagram. |
| Samantha rejected a substantial alimony offer from Chaitanya, emphasizing her independence. |
| Samantha and Naga Chaitanya were known as 'ChaySam' by fans. |
| She launched her film production company and co-owns the fashion label Saaki. |
| Samantha is one of the highest-paid South Indian actresses and was a chief guest at an Independence Day Parade. |
| She was a guest on 'MTV Hustle 3.0' and will star in the Hindi remake of 'Citadel'. |
| Samantha was seen smoking in a video with Naga and drinks at events. |
| A fan built a temple in her honor in Andhra Pradesh on her birthday. |
| She has graced the covers of magazines like Elle, Filmfare, and Cosmopolitan. |
| Samantha adores animals and has two pet dogs. |
| She is religious and has strong faith in God. |
| Samantha shares podcasts on her YouTube channel. |
| She battles myositis, a condition causing muscle inflammation, weakness, and pain. |
| Samantha underwent a nose job to enhance her appearance. |
