| Sherfane Rutherford began playing cricket at just 6 years old for Enmore's village team. |
| His first-class debut was on April 15, 2017, for Guyana in the 2016–17 Regional Four-Day Competition at Providence, Rhode Island. |
| He represented West Indies B in the Global T20 Canada tournament in June 2018, emerging as the top run-scorer with 230 runs in eight games. |
| Rutherford scored 46 runs off 21 balls for Bengal Tigers in the 2018 T10 Cricket League. |
| In his first T20I match against Bangladesh on December 22, 2018, playing for West Indies, he scored 2 runs off 6 deliveries. |
| Delhi Capitals bought him for Rs 2 crore in the 2019 IPL auction. |
| He was traded to Mumbai Indians from Delhi Capitals in 2019 for Mayank Markande. |
| During a 2020 PSL match, fans criticized him for wearing Mumbai Indians' gloves instead of Karachi Kings' gloves. |
| Unsold in the 2021 IPL auction, he later joined SunRisers Hyderabad as a replacement player. |
| In IPL 2022, Royal Challengers Bangalore bought him for Rs 1 crore; however, he went unsold in the 2023 auction. |
| During an ILT20 Tournament, he hit 5 consecutive sixes off Yusuf Pathan. |
| At the GT20 Canada 2023 final, he scored 38 runs for Montreal Tigers against Surrey Jaguars, winning Player of the Match and Player of the Series awards. |
| In his debut ODI match against England, he scored 6 runs in 3 balls. |
| He was bought by Kolkata Knight Riders for Rs. 1.50 crore in the 2024 IPL Auction. |
| Rutherford achieved his first ODI half-century against England on December 6, 2023, with 63 runs. |
| His debut ODI fifty came against Australia on February 13, 2024, scoring 67 not out in 40 balls. |
| In March 2024, he left PSL season 9 midway due to personal reasons. |
